Hyperpigmented palmar plaque: An unexpected diagnosis of Bowen disease

A middle-aged lady with an asymptomatic, hyperpigmented plaque on the thigh: what is your diagnosis?

CLINICAL PRESENTATIONA 44-year-old lady came to a dermatology clinic due to an asymptomatic, hyperpigmented plaque on her right thigh since 4 months ago. On physical exam, hypertrichosis on the lesion was notable (Figure 1). Rubbing the lesion resulted in erythema and edema of the lesion. She had no systemic disease and her family history was unremarkable.

Hyperpigmented plaque on the foot of a Kenyan patient.

An unexpected diagnosis.

Starry Liver: An Unexpected Diagnosis

A 65-year-old man presented with mildly elevated gamma-glutamyltranspeptidase (GGT) serum level on blood tests done for general check-up, and the finding of hepatomegaly and diffuse heterogeneity of the hepatic parenchyma on abdominal ultrasound. The patient’s history included essential hypertension treated with angiotensin converting enzyme-inhibitors. The patient had no other features of the ...

Cardiac angiosarcoma: an unexpected diagnosis

Cardiac angiosarcoma is a rare entity. The incidence through autopsy findings ranges between 0.001% and 0.03%. The disease usually presents with non-specific symptoms, although asymptomatic cases are frequent; therefore, diagnosis is unexpected and consequently delayed. The authors report the case of a middle-aged man with a recent onset cough and dyspnea. He sought medical care several times w...